Does TRT Help with Weight Loss? Who Should Seek Treatment?

Testosterone replacement therapy (TRT) is more than a hormone treatment. It’s a science-backed approach to restoring metabolic balance, building lean muscle, and reversing age-related weight gain in men with low testosterone. While it’s natural for testosterone levels to decline with age, this drop often comes with fatigue, loss of strength, and increased difficulty maintaining a healthy weight. For men with low or suboptimal testosterone, TRT can play a significant role in weight management, fat loss, and muscle development.

What is Testosterone? 

Testosterone is a hormone that drives development of the following in men: 

• Physical characteristics - muscle growth, vocal tone, body frame, facial hair  

• Sexual function - libido, sperm production and potency 

• Metabolic health - Helps regulate body fat distribution and blood sugar levels 

• Development of the Reproductive Organs 

• Cognitive function - leads to clearer thinking, mood, better memory, and decisiveness

Although testosterone is most often discussed in relation to men, women also produce small amounts that are essential for mood, metabolism, and sexual health. TRT is primarily used for men, but in select cases, it can also benefit women with low androgen levels when prescribed by a medical professional.

Symptoms of Low Testosterone 

Low testosterone, or hypogonadism, can cause a wide range of symptoms that affect daily life and long-term health:



• Low libido and potency


• Reduced energy and endurance


• Decreased muscle mass and strength
Increased body fat, especially abdominal fat.


• Mood changes, irritability, and poor concentration



Anyone experiencing these symptoms should have their hormone levels checked through bloodwork. A qualified medical provider can evaluate testosterone, estrogen, and related hormones to determine whether TRT is appropriate.

Low Testosterone and Weight 

As men age, testosterone levels can decline naturally. This leads to increased fat storage and decreased muscle mass. Low testosterone slows metabolism and energy levels, which can result in less physical activity and more fat accumulation, particularly in the abdominal region.



This creates a feedback loop: excess body fat increases aromatase activity, which converts testosterone into estrogen, further lowering testosterone levels. Over time, this imbalance contributes to weight gain, fatigue, and decreased motivation.



Restoring testosterone to physiologic levels can break this cycle. Balanced testosterone levels promote lean muscle growth, fat loss, and improved energy, which together create a healthier body composition and easier weight management.

TRT & Weight Loss: What does the research show?

Let’s look into some of the clinical results on the link between TRT and weight loss. 

An article published in Obesity Reviews states the following: “Testosterone replacement therapy demonstrates beneficial effects on measures of obesity that are partially explained by both direct metabolic actions on adipose and muscle and also potentially by increasing motivation, vigour and energy allowing obese individuals to engage in more active lifestyles.”

A review published in the Current Opinion in Endocrinology, Diabetes and Obesity states that “... testosterone therapy in obese men with testosterone deficiency offers a well tolerated and effective therapy and produces sustained and significant weight loss. Testosterone therapy increases LBM [Lean Body Mass], reduces fat mass and produces sustained and significant weight loss, reduction in waist circumference and BMI.”

In a randomized controlled trial published in The Journal of Cachexia, Sarcopenia and Muscle found that among older men with hypergonadism, lean muscle mass and bone mineral density decreased less in those on TRT than in the placebo group. 

A clinical trial published in The European Journal of Endocrinology found that “TRT was effective for waist circumference and BMI,” with no difference in adverse events found between the TRT and placebo group. 

Studies continue to be published that show a strong correlation between a balanced endocrine system and weight loss, along with higher maintenance of bone density and muscle. The body naturally produces less testosterone when males get into their mid to late thirties, and as time passes, endogenous levels of testosterone continue to reduce. TRT provides a way of supplementing T levels both to alleviate negative symptoms that go along with low testosterone and to assist patients in their weight loss journey. While some myths about TRT continue to circulate, research nonetheless shows that it is an effective treatment. 

Now, let’s look at a few treatment regimens that can help increase testosterone. 

How to Increase Testosterone  

The goal of increasing testosterone should include both TRT and lifestyle changes. 

Testosterone Replacement Therapy 

After carefully analyzing an individual’s blood samples to determine whether there is in fact a deficiency of testosterone in the body, Lucidity Health’s next step is to recommend a TRT treatment regimen from a number of tiered plans comprised of several or more of the following: 

• Injectable testosterone

• TRT in MCT oil

• TRT grapeseed oil

• Testosterone cream 

• Nandrolone (Deca) 

• Human chorionic gonadotropin

• Enclomiphene Tablets

• Oxandrolone

These come along with unlimited consults and supplies, not only to ensure that patients have all the information and guidance they need, but also in case there are any side effects that need to be discussed with a doctor. 

We encourage patients to learn more about the ease of use of testosterone injections. They’re simple, easy, and far more painless than they might sound! 

Patients typically see the side effects of low testosterone subside soon after treatment begins. Weight loss is a gradual process that could require months to see tangible results. However, as shown above, patients can expect the benefits of TRT on weight loss to be significant and palpable, while also assisting with muscle growth and retention as the process unfolds.  

Natural Testosterone Enhancement Solutions 

Additionally, it would be remiss to not mention that lifestyle is another important piece of the puzzle. Exercise and a balanced diet are important aspects of managing weight, as are ensuring that the body has the support of vitamin D, among other vitamins and nutrients that support a robust hormonal balance.

Weight training and exercise-induced weight loss are likely to also promote an increase in testosterone, which will act as a natural supplement to any externally administered TRT, as will managing stress and improving sleep.  

TRT and Weight Loss with Lucidity Health 

Lucidity Health specializes in hormone optimization with a patient-first approach. The process begins with a simple blood draw, completed in-office, at LabCorp, or via a convenient at-home test. Once results are reviewed, a provider designs a personalized TRT plan that fits your goals and physiology.



Every treatment plan includes:



• Comprehensive lab evaluation and interpretation


• Unlimited follow-ups and supplies


• Ongoing hormone optimization

• Body composition tracking using our advanced InBody Scanner

Typically, insurance does not cover TRT, which allows Lucidity Health to provide transparent pricing and individualized care without delays or restrictions.

Begin your TRT Journey with Lucidity Health

Balanced testosterone can transform the way you feel, perform, and look. From increasing muscle and energy to supporting sustainable fat loss, TRT offers a proven path toward better health and vitality.



At Lucidity Health, our clinical team combines expertise with compassionate care to help you regain your strength and confidence. Schedule your hormone assessment today and take the first step toward a healthier, more energized you!